Cardiac Progenitor Cells in Basic Biology and Regenerative Medicine

Regenerative biology and medicine.

The replacement of damaged tissues and organs with tissue and organ transplants or bionic implants has serious drawbacks. There is now emerging a new approach to tissue and organ replacement, regenerative biology and medicine. Regenerative biology seeks to understand the cellular and molecular differences between regenerating and non-regenerating tissues. Regenerative medicine seeks to apply th...

Amniotic Fluid Progenitor Cells and Their Use in Regenerative Medicine

Developmental and regenerative biology of multipotent cardiovascular progenitor cells.

Our limited ability to improve the survival of patients with heart failure is attributable, in part, to the inability of the mammalian heart to meaningfully regenerate itself. The recent identification of distinct families of multipotent cardiovascular progenitor cells from endogenous, as well as exogenous, sources, such as embryonic and induced pluripotent stem cells, has raised much hope that...

Cardiac Regenerative Medicine

ociety is increasingly affected by degenerative diseases that need to be treated by modern medicine. In the advanced stages of such diseases, modalities for cure are often not available. Heart disease is the primary cause of death throughout the world, despite dramatic improvements that have been made in the treatment of cardiovascular diseases over the past decades. At present, heart transplan...

Platelet interaction with progenitor cells: potential implications for regenerative medicine.

Circulating endothelial progenitor cells have been shown to instigate new vessel formation via angiogenesis and neovascularisation and to induce ongoing vascular and tissue repair by domiciliation to sites of vascular or tissue damage. However, the mechanisms that recruit circulating endothelial progenitor cells towards vascular lesions and regulate repair mechanisms of ischemic peripheral orga...